Why does glomerular filtration rate decreased

Trans Am Clin Climatol Assoc. Richard J. Glassock , M. Author information Copyright and License information Disclaimer. Laguna Niguel, CA. Correspondence and reprint requests: Richard J. This article has been cited by other articles in PMC. Abstract The process of glomerular filtration of plasma fluid has been known for over years and the measurement of the rate of its formation glomerular filtration rate, GFR has been possible for over 80 years.

TRUTHS The process of glomerular filtration has been recognized for over years, since Ludwig in first proposed the physico-mechanical formation of a protein-free ultrafiltrate by the renal glomeruli 1. Open in a separate window. Footnotes Potential Conflict of Interest: None disclosed. Smith HW. New York: Oxford University Press; Renal excretion of inulin, creatinine and xylose in normal dogs. Proc Soc Exp Biol Med. The Kidney in Health and Disease.

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GFR is also affected by various factors such as gender, age, and size. There is variation amongst people who have similar attributes still GFR differ for them. Then, this value is multiplied by 1.

What are the normal ranges of GFR? The reasons why your GFR decreases If you have decreased GFR, the doctor may do some clinical examination to know the underlying cause of the abnormal result. Following can be the reason why your GFR may reduce: You have been taking any new medication such as anti-inflammatory, diuretics, antibiotics, or fluid tablets from a long time that too without the prescription from your consultant.

Dehydration is another factor that may cause GFR to decrease, at least temporarily. This is because our kidneys need water in order to clean the blood for waste and in the absence of water, they may not work largely. If you have been taking any procedures that include administering contrast and dyes such as angiograms or CT scan.

Blood tests to check your hemoglobin levels and white cell count, in order to closely monitor the excretion of electrolyte and waste by your kidneys. Urine samples to with a dipstick to check for the presence of protein or blood cells in your urine. Ultrasound to image your kidneys for abnormalities such as swelling, size of the kidneys, and any obstruction in the urinary tract membrane. If you have been onto medications that need to be excreted through the kidneys also damages the function and nature of your kidney.

To prepare for the blood testing and to ensure that the results are accurate, most medical professionals would recommend refraining from taking medications like antibiotics and stomach acid medications. Before the test, it is important to discuss with a doctor all of the medications that one may be taking in order to determine whether any of the medications may be a problem.

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